A soothing serum that protects sensitive skin and smooths the first lines
Bioderma Sensibio Defensive Serum is a soothing anti-ageing serum for sensitive and sensitised skin. Stress, pollution and temperature changes make fragile skin more reactive, and over time this shows as fine lines, dehydration and dullness. This fragrance-free serum works on both fronts. Hydrolyzed hyaluronic acid hydrates lastingly and plumps the skin, which softens the look of fine lines. An antioxidant complex of carnosine, red sage extract and vitamin E protects against daily aggressions, while palmitoyl tetrapeptide-10 and soothing plant sugars help calm reactivity and reinforce the skin barrier. It comforts the skin as soon as it is applied, and day after day the complexion looks smoother and more luminous. According to Bioderma, it can also be used before and after aesthetic procedures.
The texture
A fresh, light serum that spreads easily and absorbs in seconds, with no greasy or sticky finish. It layers well under moisturiser and sunscreen in the morning and under a richer cream at night. Skin feels calmer and more comfortable right after application, which makes it easy to stick with twice a day, even on days when your skin feels reactive.
Who it suits
- Sensitive skin starting to show fine lines
- Reactive skin that tingles or feels tight
- Dehydrated, dull complexions
- Anyone who wants an anti-ageing serum without fragrance
Worth knowing before you buy: a serum on its own may not be enough for dry skin; follow it with a moisturiser such as Sensibio Defensive Rich. The formula contains soybean oil, so skip it if you react to soy.
How long a bottle lasts
Two to three drops morning and evening use roughly half a millilitre a day, so the 30ml bottle lasts about two months of twice-daily use.
Complete the routine

Sensibio Defensive Rich
A richer soothing cream to seal in the serum.
Shop →
Sensibio H2O
The gentle micellar cleanser for sensitive skin.
Shop →Characteristics
- Texture: serum
- Skin type: all skin types, including sensitive
- Skin concerns: fine lines and wrinkles, dehydration, dullness, sensitivity
- When to apply: morning and evening
- Main benefits: hydrates lastingly, soothes, protects, strengthens the skin barrier, smooths fine lines
- Formulated without: fragrance, parabens, alcohol
How to use
Apply morning and evening to a clean, dry face and neck, then follow with your moisturiser. In the morning, finish with sunscreen.
Active ingredients
- Hydrolyzed hyaluronic acid: hydrates and plumps
- Carnosine, red sage extract and vitamin E: antioxidant protection
- Palmitoyl tetrapeptide-10: helps reduce skin reactivity
- Rhamnose and biosaccharide gum-1: soothing plant sugars that comfort the skin
- Squalane: softens and supports the skin barrier
Ingredients
AQUA/WATER/EAU · GLYCERIN · BUTYLENE GLYCOL · C15-19 ALKANE · SQUALANE · CELLULOSE · C20-22 ALKYL PHOSPHATE · C20-22 ALCOHOLS · PENTYLENE GLYCOL · 1,2-HEXANEDIOL · CAPRYLYL GLYCOL · CARNOSINE · POLYACRYLATE CROSSPOLYMER-6 · MALTODEXTRIN · XANTHAN GUM · MANNITOL · XYLITOL · TOCOPHEROL · SALVIA MILTIORRHIZA ROOT EXTRACT · RHAMNOSE · BIOSACCHARIDE GUM-1 · CITRIC ACID · GLYCINE SOJA (SOYBEAN) OIL · HYDROLYZED HYALURONIC ACID · SODIUM HYDROXIDE · PALMITOYL TETRAPEPTIDE-10
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: NAOS (Bioderma)
Address: 355 rue Pierre-Simon Laplace, 13290 Aix-en-Provence, France
EAN: 3701129805374
