An exfoliating serum for clogged pores and uneven texture
Avène Cleanance Comedomed Intensive Serum is an intensive serum for oily, blemish-prone skin with blackheads and clogged pores. It is built around 25% Comedoclastin, a milk thistle extract, with 3% glycolic acid to smooth texture, bakuchiol to balance sebum and ascorbyl glucoside for radiance. It helps pores look clearer and skin feel smoother.
The texture
A light, clear serum in a dropper bottle that absorbs quickly.
Who it suits
- Oily skin with blackheads and enlarged-looking pores
- Blemish marks and uneven texture
- Teens and adults from age 12
Worth knowing before you buy: It contains 3% glycolic acid and isopropyl alcohol, so start slowly and use sun protection during the day. Very dry or reactive skin may find it too active.
Complete the routine

Cleanance Cleansing Gel
Purifying wash for oily, blemish-prone skin.
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Cleanance SPF50+
Daily sun protection for oily skin.
Shop →Characteristics
- Texture: light serum
- Skin type: oily, blemish-prone skin
- Concerns: blackheads, clogged pores, uneven texture
- When to apply: morning and evening on cleansed skin
- Age: from 12 years
- Main benefits: exfoliating, purifying, smoothing
How to use
Apply morning and evening to cleansed skin, avoiding the eye area. Use sun protection during the day. If it feels uncomfortable, apply less often.
Active ingredients
- Comedoclastin (25%): milk thistle extract that targets blackheads and blemishes
- Glycolic acid (3%): exfoliates and smooths texture
- Bakuchiol: helps regulate sebum
- Ascorbyl glucoside (2%): a stable vitamin C form for radiance
Ingredients
Avene Aqua (Avene Thermal Spring Water) · Isopropyl Alcohol · PEG-6 · Glycerin · Glycolic Acid · Silybum Marianum Fruit Extract · Aqua (Water) · Ascorbyl Glucoside · Acacia Senegal Gum · Bakuchiol · Beta-Caryophyllene · Citric Acid · Helianthus Annuus (Sunflower) Seed Oil · Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer · Polysorbate 60 · Sodium Citrate · Sodium Hydroxide · Sorbitan Isostearate · Tocopherol · Xanthan Gum
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: Laboratoires Dermatologiques Avène
Address: Les Cauquillous, 81506 Lavaur Cedex, France
EAN: 3282770401448
