A 15-day peel-effect cream for acne flare-ups and the marks they leave
Avène Cleanance Comedomed Peeling is an intensive peel-effect cream for acne-prone skin during breakouts, made to reduce the size and number of spots and fade the marks they leave behind. It combines three actives: 6% glycolic acid, which exfoliates and renews the skin surface, Comedoclastin (a milk thistle extract, 7%), which helps regulate sebum and unclog pores, and 0.1% retinaldehyde, a retinoid that smooths skin texture and helps fade red and brown marks. Avène Thermal Spring Water, the first ingredient, soothes. It is used as a short course, in the evening, for up to 15 days in a row.
The texture
A light, pink-tinted cream that spreads easily and absorbs without a greasy film. A mild tingling on application is normal with glycolic acid and retinaldehyde, and it fades in a few minutes.
Who it suits
- Adult or teen acne-prone skin during a breakout
- Blackheads, spots and clogged pores
- Red or brown marks left by old blemishes
- Oily to combination skin that needs a short, targeted course
Worth knowing before you buy: glycolic acid and retinaldehyde make the skin more sun-sensitive and can cause dryness or redness, especially on sensitive skin. Wear a high SPF every day, don't combine it with other exfoliating or retinoid products, and avoid it during pregnancy. It contains alcohol.
How long one tube lasts
One 15-day course uses only part of the 40ml tube, so a tube typically covers two to three courses spaced out over the year.
Complete the routine

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Soothes and hydrates skin dried out by acne treatments.
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Cleanance SPF50+
A matte sunscreen for blemish-prone skin.
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- Texture: light cream
- Skin type: oily, combination and acne-prone skin
- Skin concerns: acne breakouts, blackheads, clogged pores, post-blemish marks
- When to apply: in the evening, for up to 15 days
- Main benefits: reduces the size and number of blemishes, exfoliates, unclogs pores, fades post-acne marks, smooths skin texture
How to use
Apply once a day in the evening to clean, dry skin on the whole face, avoiding the eye area, lips and nostrils. Use for up to 15 consecutive days, then switch back to your usual Cleanance care. Use a high SPF every morning during and after the course.
Active ingredients
- Glycolic acid 6%: exfoliates and renews the skin surface
- Comedoclastin 7% (milk thistle fruit extract): helps regulate sebum and unclog pores
- Retinaldehyde 0.1%: smooths texture and helps fade post-acne marks
- Avène Thermal Spring Water: soothes and calms
Ingredients
AVENE THERMAL SPRING WATER (AVENE AQUA) · CAPRYLIC/CAPRIC TRIGLYCERIDE · ISODODECANE · GLYCOLIC ACID · ISOPROPYL ALCOHOL · PEG-6 · GLYCERIN · HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER · WATER (AQUA) · SODIUM HYDROXIDE · GLYCERYL STEARATE · PEG-100 STEARATE · POLYMETHYL METHACRYLATE · ARACHIDYL ALCOHOL · ARACHIDYL GLUCOSIDE · BEHENYL ALCOHOL · HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL · POLYSORBATE 60 · RED 33 (CI 17200) · RETINAL · SILYBUM MARIANUM FRUIT EXTRACT · SORBITAN ISOSTEARATE · TOCOPHEROL
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: Laboratoires Dermatologiques Avène
Address: Les Cauquillous, 81506 Lavaur Cedex, France
EAN: 3282770395365