An overnight repair cream for skin that reacts to almost everything
La Roche-Posay Toleriane Dermallergo Night Cream is a soothing night moisturizer for sensitive and allergy-prone skin, built on a minimal, fragrance-free formula. It contains Sphingobioma, a probiotic-derived ingredient that supports the skin microbiome and strengthens the skin barrier, together with Neurosensine and 2% niacinamide to calm discomfort. Tightness, redness and dryness are relieved straight away, and the skin is repaired overnight, with hydration for up to 48 hours.
The texture
A soft gel-cream that melts in quickly and leaves no greasy film on the pillow. It is completely fragrance-free.
Who it suits
- Sensitive or allergy-prone skin that reacts to many products
- Skin that feels tight, itchy or red by the end of the day
- Anyone simplifying a routine after a reaction
- Teens and adults, from 10 years old
Worth knowing before you buy: It is a comforting moisturizer, not an anti-ageing cream, so it has no retinol or exfoliating acids. Pair it with the Dermallergo day cream in the morning for round-the-clock soothing.
How long one tube lasts
Used every evening on face and neck, the 40ml tube lasts around two months.
Complete the routine

Dermallergo Day Cream
The daytime partner for reactive skin.
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Dermallergo Eye Cream
Soothing care for sensitive eye contours.
Shop →Characteristics
- Texture: gel-cream
- Skin type: all skin types, including sensitive and allergy-prone
- Skin concerns: sensitivity, redness, tightness, dryness
- When to apply: evening
- Age: 10+
- Main benefits: soothes instantly, repairs the skin barrier overnight, supports the skin microbiome, 48-hour hydration
- Formulated without: fragrance, alcohol
How to use
Apply in the evening to clean, dry face and neck.
Active ingredients
- Sphingobioma: probiotic-derived ingredient that supports the skin microbiome and the skin barrier
- Neurosensine: reduces feelings of discomfort and skin reactivity
- Niacinamide (2%): calms the skin and helps reinforce the skin barrier
- Vitamin B6: soothes and helps minimise redness
Ingredients
AQUA / WATER / EAU · GLYCERIN · BUTYLENE GLYCOL · PROPANEDIOL · BUTYROSPERMUM PARKII BUTTER / SHEA BUTTER · PENTYLENE GLYCOL · SQUALANE · NIACINAMIDE · AMMONIUM POLYACRYLOYLDIMETHYL TAURATE · PYRIDOXINE HCl · POLYSORBATE 20 · ZEA MAYS STARCH / CORN STARCH · SALVIA MILTIORRHIZA ROOT EXTRACT · ALLANTOIN · GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER · SODIUM HYDROXIDE · SPHINGOMONAS FERMENT EXTRACT · HYDROXYACETOPHENONE · CAPRYLYL GLYCOL · CITRIC ACID · TRISODIUM ETHYLENEDIAMINE DISUCCINATE · ACETYL DIPEPTIDE-1 CETYL ESTER · XANTHAN GUM · TOCOPHEROL
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: La Roche-Posay Laboratoire Dermatologique
Address: 86270 La Roche-Posay, France
EAN: 3337875800853
