Retinol for sensitive skin, without the usual irritation
La Roche-Posay Retinol B3 Serum is an anti-aging night serum for skin that usually finds retinol too harsh. It pairs pure and gradual-release retinol, which boost cell renewal, with niacinamide (vitamin B3) and 10% glycerin to hydrate and soothe. Over time, fine lines and wrinkles look softer and skin texture and tone more even.
The texture
A light, silky serum that spreads easily and absorbs quickly under a moisturiser.
Who it suits
- First-time retinol users with sensitive skin
- Fine lines, loss of firmness and uneven texture
- Adults from around 30
Worth knowing before you buy: it contains fragrance and denatured alcohol, and retinol makes skin more sensitive to the sun, so wear SPF every morning.
Complete the routine

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Anthelios UVMune 400
Daily SPF50+ while using retinol.
Shop →Characteristics
- Texture: serum
- Skin type: all skin types, including sensitive
- Skin concerns: fine lines, wrinkles, loss of firmness, uneven texture
- When to apply: evening
- Age: 30+
- Main benefits: reduces wrinkles, refines and renews the complexion, hydrates and soothes, non-comedogenic
- Formulated without: parabens, sulfates
How to use
In the evening, apply a few drops to clean, dry skin on the face, avoiding the eye area, then follow with a moisturiser. Start every other night for the first weeks. Use SPF every morning.
Active ingredients
- Pure and gradual-release retinol: boost cell renewal to smooth lines and refine texture
- Niacinamide (vitamin B3): soothes and strengthens the skin barrier
- Glycerin (10%): hydrates and protects from irritation
- Adenosine: helps smooth wrinkles
Ingredients
AQUA/WATER · GLYCERIN · CYCLOHEXASILOXANE · ALCOHOL DENAT. · PENTYLENE GLYCOL · NIACINAMIDE · DIMETHICONE · GLYCINE SOJA OIL / SOYBEAN OIL · PPG-6-DECYLTETRADECETH-30 · SODIUM HYALURONATE · RETINOL · ADENOSINE · AMMONIUM POLYACRYLOYLDIMETHYL TAURATE · CAPRYLYL GLYCOL · CITRIC ACID · TRISODIUM ETHYLENEDIAMINE DISUCCINATE · XANTHAN GUM · POLYSILICONE-11 · RETINYL PALMITATE · TOCOPHEROL · PHENOXYETHANOL · PARFUM/FRAGRANCE
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: La Roche-Posay Laboratoire Dermatologique
Address: 86270 La Roche-Posay, France
EAN: 3337875694469
