A daily serum for stubborn dark spots, on every skin tone
La Roche-Posay Mela B3 Concentrated Serum is an anti-dark spot serum for all skin types and tones, perfect for age spots, sun spots and the dark marks left by acne or scars. It replaces the Pure Niacinamide 10 serum and keeps 10% niacinamide, which strengthens the skin barrier and helps reduce hyperpigmentation. Its key new ingredient is Melasyl, a patented molecule that intercepts excess melanin before it shows as a spot. LHA, retinyl palmitate and carnosine complete the non-comedogenic formula.
The texture
A light serum-gel dispensed with a dropper. Two or three drops cover the face and absorb quickly, leaving a smooth, non-sticky finish that sits well under moisturiser and sunscreen.
Who it suits
- Sun spots and age spots on the face, neck and hands
- Brown marks left after breakouts
- Uneven tone that keeps coming back after summer
- Sensitive skin that wants a well-tolerated spot serum
Worth knowing before you buy: The serum contains fragrance, retinyl palmitate and LHA. Dark spots come back quickly without sun protection, so pair it every morning with a broad-spectrum SPF such as Anthelios UVMune 400 Invisible Fluid.
How long one bottle lasts
At 2 to 3 drops once or twice a day, the 30ml bottle lasts about two months, which matches the eight weeks the brand gives for visible correction of persistent spots.
Complete the routine

Anthelios UVMune 400 Fluid
Daily SPF50+ to stop spots coming back.
Shop →
Cicaplast Baume B5+
A soothing balm for dry, irritated patches.
Shop →Characteristics
- Texture: serum-gel
- Skin type: all skin types and phototypes, including sensitive skin
- Skin concerns: dark spots, sun spots, age spots, post-acne marks, uneven tone
- When to apply: morning and/or evening
- Age: 25+
- Main benefits: reduces dark spots and helps prevent their return, evens skin tone, non-comedogenic
- Formulated without: alcohol, parabens
How to use
Before the first use, replace the cap with the dropper. Apply 2 to 3 drops to clean skin of the face, neck, décolleté or hands, morning and/or evening, and massage gently until absorbed. Avoid the eye area. Follow with moisturiser and, in the morning, a broad-spectrum sunscreen.
Active ingredients
- Niacinamide (10%): strengthens the skin barrier and helps limit the transfer of pigment to skin cells
- Melasyl (2-mercaptonicotinoyl glycine): patented molecule that intercepts excess melanin before spots form
- LHA (capryloyl salicylic acid): gentle exfoliation for a more even surface
- Retinyl palmitate and carnosine: support skin renewal and an even-looking complexion
- Dipotassium glycyrrhizate: soothes the skin
Ingredients
AQUA / WATER / EAU · DIMETHICONE · NIACINAMIDE · GLYCERIN · PROPYLENE GLYCOL · POLYSILICONE-11 · SILICA · BIS-PEG/PPG-16/16 PEG/PPG-16/16 DIMETHICONE · CYSTOSEIRA TAMARISCIFOLIA EXTRACT · 2-MERCAPTONICOTINOYL GLYCINE · PEG-20 METHYL GLUCOSE SESQUISTEARATE · SODIUM HYALURONATE · SODIUM HYDROXIDE · SODIUM THIOSULFATE · CARNOSINE · POLOXAMER 338 · AMMONIUM POLYACRYLOYLDIMETHYL TAURATE · DIPOTASSIUM GLYCYRRHIZATE · CAPRYLIC/CAPRIC TRIGLYCERIDE · CAPRYLOYL SALICYLIC ACID · CAPRYLYL GLYCOL · CITRIC ACID · TRISODIUM ETHYLENEDIAMINE DISUCCINATE · XANTHAN GUM · PENTYLENE GLYCOL · OCTYLDODECANOL · RETINYL PALMITATE · TOCOPHEROL · PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE · PHENOXYETHANOL · CI 17200 / RED 33 · PARFUM / FRAGRANCE
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: La Roche-Posay Laboratoire Dermatologique
Address: 86270 La Roche-Posay, France
EAN: 3337875890021
