A high-strength urea balm for thick, rough and scaly areas
Isispharma Urelia 50 is a balm for localised rough areas prone to scaling or hyperkeratosis, including skin with a tendency to psoriasis. It combines 50% urea with glycolic and lactic acids to soften and reduce thick plaques, while a complex of amino acids and a postbiotic helps restore the skin barrier and hold water in the skin. Shea butter and glycerin add comfort. In Isispharma's 28-day clinical study, 80% of users saw a significant reduction of their hyperkeratosis plaques.
The texture
A smooth, creamy balm that spreads easily on small areas and feels comfortable on fragile skin. It is fragrance-free.
Who it suits
- Thick, scaly patches on elbows, knees or heels
- Rough areas with a tendency to psoriasis
- Localised hyperkeratosis that ordinary creams do not soften
Worth knowing before you buy: at 50% urea with AHAs, it is meant for small, thickened areas, not for the face or broken skin, and it may sting at first. It also contains mineral oil and silicones.
How long one tube lasts
Used once or twice a day on a few small patches, the 40ml tube lasts around six to eight weeks, which matches the recommended course.
Complete the routine

Xerial Exfoliating Gel
A gentle peeling wash for rough, flaky skin.
Shop →
Xémose PSO Concentrate
Soothing care for larger areas prone to psoriasis.
Shop →Characteristics
- Texture: creamy balm
- Skin type: rough, thickened skin prone to scaling
- Skin concerns: scaly plaques, hyperkeratosis, psoriasis-prone skin
- When to apply: once or twice a day, for 6 to 8 weeks
- Main benefits: softens and reduces thick plaques, hydrates, helps restore the skin barrier
- Formulated without: fragrance
How to use
Apply to the areas concerned once or twice a day, for 6 to 8 weeks, until the plaques reduce. It can be combined with Urelia Gel to cleanse and gently exfoliate the skin.
Active ingredients
- Urea (50%) and AHAs (glycolic and lactic acids): soften and reduce thick plaques
- Amino acids and postbiotic complex: help restore the skin barrier and keep water in the skin
- Sodium chloride: boosts the action of urea
- Shea butter and glycerin: nourish and hydrate
Ingredients
UREA · AQUA (WATER) · PARAFFINUM LIQUIDUM (MINERAL OIL) · GLYCERIN · CYCLOPENTASILOXANE · GLYCOLIC ACID · BUTYROSPERMUM PARKII (SHEA) BUTTER · DICAPRYLYL ETHER · CYCLOHEXASILOXANE · POLYGLYCERYL-4 ISOSTEARATE · CETYL PEG/PPG-10/1 DIMETHICONE · HEXYL LAURATE · BEHENOXY DIMETHICONE · PENTYLENE GLYCOL · DIMETHICONE · SODIUM CHLORIDE · PSEUDOALTEROMONAS FERMENT EXTRACT · LACTIC ACID · CHLORPHENESIN · XANTHAN GUM · CAPRYLYL GLYCOL · ETHYLHEXYLGLYCERIN · ALANINE · PROLINE · SERINE · SODIUM PHOSPHATE · SODIUM HYDROXIDE · TOCOPHEROL · GLYCINE SOJA (SOYBEAN) OIL · PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE · CITRIC ACID
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: Isispharma France
Address: 29 avenue de la Marne, Parc des 3 Chênes, 59290 Wasquehal, France
EAN: 3401399521799
