The Hyalu B5 serum in a 50ml size, to plump fine lines and repair the skin barrier
La Roche-Posay Hyalu B5 Serum is a concentrated plumping, repairing serum for skin showing wrinkles and loss of volume, suited to sensitive skin. Its formula pairs two types of hyaluronic acid, which hydrate and help plump the skin, with vitamin B5 (panthenol), which helps repair and soothe it. Madecassoside, a molecule from Centella asiatica, helps strengthen the skin barrier. Wrinkles look filled in, fine lines are smoothed and the skin feels more elastic and comfortable.
The texture
A light, fresh gel-serum that spreads in one pass and absorbs quickly without a sticky film. It layers easily under a moisturiser or sunscreen in the morning.
Who it suits
- First wrinkles and fine lines
- Skin that has lost bounce and volume
- Sensitive skin that dislikes strong anti-ageing actives
- Dehydrated, tight-feeling skin
Worth knowing before you buy: This is the original Hyalu B5 serum, not the newer Suractivated version. It contains alcohol denat. and fragrance, low in the formula, which very reactive skin may notice. It hydrates and plumps rather than exfoliates, so it pairs well with a retinoid at night.
How long one bottle lasts
With 3 to 4 drops morning and evening, the 50ml bottle usually lasts around 3 months.
Complete the routine

Hyalu B5 Cream
Plumping, repairing anti-wrinkle cream.
Shop →
Hyalu B5 Eyes
The same duo for the eye area.
Shop →Characteristics
- Texture: gel-serum
- Skin type: all skin types, including sensitive
- Concerns: wrinkles, fine lines, loss of volume, dehydration
- When to apply: morning and evening
- Main benefits: plumps, hydrates, smooths fine lines, helps repair the skin barrier
How to use
Apply 3 to 4 drops to clean face and neck, morning and evening, and massage gently until absorbed. Follow with your moisturiser, and a sunscreen in the morning.
Active ingredients
- Hyaluronic acid (sodium hyaluronate and hydrolyzed hyaluronic acid): hydrates and helps plump the skin
- Panthenol (vitamin B5): helps repair and soothe the skin
- Madecassoside: helps strengthen the skin barrier
Ingredients
Aqua/Water · Glycerin · Alcohol Denat · Propylene Glycol · Panthenol · Pentylene Glycol · Dimethicone · PEG-6 Caprylic/Capric Glycerides · PPG-6-Decyltetradeceth-30 · Glyceryl Isostearate · Madecassoside · Sodium Hyaluronate · Ammonium Polyacryloyldimethyl Taurate · Disodium EDTA · Hydrolyzed Hyaluronic Acid · Caprylyl Glycol · Citric Acid · Xanthan Gum · Butylene Glycol · Tocopherol · Phenoxyethanol · Parfum/Fragrance
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: La Roche-Posay Laboratoire Dermatologique
Address: 86270 La Roche-Posay, France
EAN: 3337875920568
