A 10% panthenol serum that repairs a stressed skin barrier and keeps it hydrated
La Roche-Posay Cicaplast B5 Ultra-Hydrating Serum is a repairing face serum for all skin types, including sensitive and dry skin. It targets dehydration, irritation and a dull complexion, and it is suitable after cosmetic procedures such as lasers and peels. Its formula is built around 10% panthenol (vitamin B5), known for its repairing and protective action on the skin barrier. Hyaluronic acid and glycerin work together to keep the skin hydrated for 24 hours, while Aqua Posae Filiformis and La Roche-Posay Thermal Spring Water soothe, and HEPES helps smooth skin texture. According to the brand, the skin barrier starts to recover within one hour, skin quality improves after one day, and after four weeks the tone looks more even and the texture smoother.
The texture
A light, fluid serum that absorbs quickly and leaves a thin, comfortable protective film on the face. It layers easily under a moisturiser or sunscreen.
Who it suits
- Sensitive, reactive or dehydrated skin
- Skin that feels tight or irritated after retinoids or acids
- Skin recovering from peels or laser treatments
- Dull, uneven skin that needs comfort
Worth knowing before you buy: the formula contains alcohol (listed fourth), which some very reactive skins may notice. For very dry or cracked patches, follow with Cicaplast Baume B5+.
How long one bottle lasts
One or two drops morning and evening are enough for the face and neck, so a 30ml bottle lasts about two months.
Complete the routine

Cicaplast Baume B5+
A soothing balm to seal in the serum.
Shop →
Anthelios UVMune 400 Fluid
Fragrance-free SPF50+ for sensitised skin.
Shop →Characteristics
- Texture: serum
- Skin type: all skin types, including sensitive
- Skin concerns: fragile skin, irritation, discomfort, dullness, dehydration
- When to apply: morning and evening
- Age: 18+
- Main benefits: repairs the skin barrier, hydrates for 24 hours, soothes redness and irritation, smooths skin texture
- Formulated without: fragrance, parabens
How to use
Apply one to two drops to the face and neck morning and evening. Wait one minute before applying other skincare products.
Active ingredients
- Panthenol (vitamin B5) 10%: repairs and protects the skin barrier
- Hyaluronic acid and glycerin: hydrate the skin for 24 hours
- Aqua Posae Filiformis (vitreoscilla ferment) and Thermal Spring Water: soothe the skin
- HEPES: helps smooth and even out skin texture
Ingredients
AQUA / WATER / EAU · PANTHENOL · GLYCERIN · ALCOHOL DENAT. · DIMETHICONE · HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID · PEG-20 METHYL GLUCOSE SESQUISTEARATE · SODIUM HYALURONATE · AMMONIUM POLYACRYLOYLDIMETHYL TAURATE · CAPRYLYL GLYCOL · VITREOSCILLA FERMENT · CITRIC ACID · XANTHAN GUM · OCTYLDODECANOL · TOCOPHEROL · PHENOXYETHANOL
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: La Roche-Posay Laboratoire Dermatologique
Address: 86270 La Roche-Posay, France
EAN: 3337875837804