A daily anti-aging cream that targets glycation, the hidden cause of lost firmness
ISDIN Isdinceutics A.G.E. Reverse Day is an anti-aging day cream for mature skin that has lost firmness and elasticity. It works on three fronts. Carnosine helps slow down glycation, the process in which sugars stiffen the skin's collagen and elastin fibers over time. Reticulated hyaluronic acid and Syn-Hycan, a peptide, help remodel the skin and keep it hydrated for 24 hours. Exo-P, a marine ferment, forms a protective barrier against pollution. In ISDIN's user test, 80% of women said their skin felt firmer and more moisturized, with a measured 34% improvement in firmness.
The texture
A lightweight cream that absorbs completely, without a sticky or shiny finish, so it layers well under sunscreen and makeup. It has a light, fresh scent.
Who it suits
- Mature skin losing firmness and elasticity
- Wrinkles and a less defined facial contour
- City dwellers exposed to pollution
- Normal to combination skin that dislikes rich creams
Worth knowing before you buy: this cream has no SPF, so follow it with a sunscreen every morning, like the FotoUltra Spot Prevent below. It contains fragrance and colorants.
How long one jar lasts
A small amount, about the size of a hazelnut, covers the face and neck. Used every morning, the 50ml size lasts around two months.
Complete the routine

FotoUltra 100 Spot Prevent
Very high sun protection to finish the routine.
Shop →
FotoUltra 100 Active Unify
SPF50+ that also targets dark spots.
Shop →Characteristics
- Texture: light cream
- Skin type: mature skin, normal to combination
- Concerns: loss of firmness, wrinkles, pollution
- When to apply: every morning
- Main benefits: anti-glycation, firming, 24h hydration, protects against pollution
- Formulated without: parabens
How to use
Every morning, apply to clean, dry skin on the face and neck and spread until fully absorbed. Finish with a broad-spectrum sunscreen.
Active ingredients
- Carnosine: helps slow down glycation of collagen and elastin
- Reticulated hyaluronic acid: long-lasting hydration and a plumper look
- Syn-Hycan (tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate): supports the skin's natural hyaluronic acid
- Exo-P (Alteromonas ferment extract): protects the skin against pollution
- Niacinamide: supports the skin barrier and evens out tone
Ingredients
AQUA (WATER) · BUTYLENE GLYCOL · ISODECYL NEOPENTANOATE · PROPANEDIOL · NIACINAMIDE · GLYCERIN · BETAINE · CAPRYLIC/CAPRIC TRIGLYCERIDE · SILICA · DIMETHICONE · HYDROGENATED POLYISOBUTENE · STEARYL ALCOHOL · OCTYLDODECANOL · DIPENTAERYTHRITYL HEXACAPRYLATE/HEXACAPRATE · TRIDECYL TRIMELLITATE · PHENYLPROPANOL · AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER · ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER · CAPRYLYL GLYCOL · PARFUM (FRAGRANCE) · CETEARYL ALCOHOL · POTASSIUM OLIVOYL HYDROLYZED OAT PROTEIN · GLYCERYL STEARATE · CARNOSINE · TRIDECYL STEARATE · NEOPENTYL GLYCOL DICAPRYLATE/DICAPRATE · GLYCERYL OLEATE · PENTYLENE GLYCOL · SODIUM HYALURONATE CROSSPOLYMER · DISODIUM EDTA · PEG-8 · ALTEROMONAS FERMENT EXTRACT · HYDROXYPROPYL CYCLODEXTRIN · TETRADECYL AMINOBUTYROYLVALYLAMINOBUTYRIC UREA TRIFLUOROACETATE · TOCOPHEROL · BENZYL ALCOHOL · POTASSIUM SORBATE · SODIUM BENZOATE · ASCORBYL PALMITATE · MAGNESIUM CHLORIDE · ALCOHOL DENAT. · ASCORBIC ACID · CITRIC ACID · PALMITOYL TRIPEPTIDE-38 · CI 15985 · CI 19140
Formulations are updated by the manufacturer from time to time. Always check the packaging you receive.
Manufacturer information
Brand: ISDIN S.A.
Address: Provençals 33, 08019 Barcelona, Spain
EAN: 8470001812353
